drugset / Trial / NCT04488744
Smoking by IV Pulsed Nicotine
RandomizedCrossoverDouble-blindHealth-services research
Summary
To establish a dose-effect curve for nicotine's abuse potential as a function of nicotine dose and delivery rate. Pulsed IV nicotine administration will be used as it closely matches nicotine delivery by inhaled tobacco use.
Timeline
- Start
- 2019-11-15
- Primary completion
- 2021-04-28
- Completion
- 2021-05-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nicotine | Unknown | 0.2 mg | Intravenous |
| Subject | Nicotine | Unknown | 1 mg | Intravenous |
Indications
No indication recorded.