drugset / Trial / NCT04491370

Autologous Stem Cell Transplant Followed by Polatuzumab Vedotin in Patients With B-cell Non-Hodgkin and Hodgkin Lymphoma

NCT04491370

Phase 1/2 Recruiting 20 enrolled New York Medical College
NaSingle-groupOpen-labelTreatment

Summary

Patients will receive one of two conditioning regimens (BEAM or CBV) before receiving an autologous stem cell transplant (ASCT). If patients achieve either complete, partial, or stable response following ASCT, they will receive an IV dose of Polatuzumab Vedotin once every 21 days until they receive 8 doses. After Polatuzumab Vedotin therapy is completed, patients will be followed every 4 months for about 2 years.

Timeline

Start
2021-08-01
Primary completion
2026-08-15
Completion
2027-08-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Polatuzumab Vedotin Other / unclassified Intravenous