drugset / Trial / NCT04492488

A Study of MRG002 in Patients with HER2-Positive Advanced Solid Tumors and Locally Advanced or Metastatic Gastric/Gastroesophageal Junction (GEJ) Cancer

NCT04492488

Phase 1/2 Active not recruiting 129 enrolled Shanghai Miracogen Inc.
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The objective of this study is to assess the safety, efficacy, and pharmacokinetics of MRG002, as well as the immunogenicity as defined by the incidence of anti-drug antibody (ADA) of MRG002 in patients with HER2-positive advanced solid tumors and locally advanced or metastatic gastric/gastroesophageal junction (GEJ) cancer.

Timeline

Start
2021-05-24
Primary completion
2022-10-18
Completion
2024-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject TRASTUZUMAB VEDOTIN Unknown 2.2 mg/kg Intravenous
Subject TRASTUZUMAB VEDOTIN Unknown 2.6 mg/kg Intravenous