drugset / Trial / NCT04497142
Effect of Perampanel on Peritumoral Hyperexcitability in HGG
Phase 1/2
Completed
12 enrolled
Dana-Farber Cancer Institute
Eisai Inc. · collabNational Cancer Institute (NCI) · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this research study is to learn more about seizures in people with primary brain tumors. It will evaluate whether an antiseizure medication decreases hyperexcitability activity around tumors and prevents seizures. The procedure and study drug involved in this study are: * Electrocorticography * Perampanel (Fycompa)
Timeline
- Start
- 2020-11-05
- Primary completion
- 2023-05-16
- Completion
- 2023-05-16
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Perampanel | Small molecule | — | Oral |
| Comparator | Levetiracetam | Other / unclassified | — | — |