drugset / Trial / NCT04499586
A Study of Radiotherapy Combined With Raltitrexed and Irinotecan in Metastatic or Locally Recurrent Colorectal Cancer
NaSingle-groupOpen-labelTreatment
Summary
The study evaluates the effectiveness of radiotherapy combined with raltitrexed and irinotecan in treating patients who have metastatic or locally recurrent colorectal cancer that has not responded to fluorouracil. The patients will receive radiotherapy combined with raltitrexed and irinotecan, and then the surgeons will evaluate whether they should receive a surgery.
Timeline
- Start
- 2019-01-01
- Primary completion
- 2020-08-01
- Completion
- 2020-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Irinotecan | Small molecule | 65 mg/m2 | Intravenous |
| Subject | Irinotecan | Small molecule | 80 mg/m2 | Intravenous |
| Subject | Raltitrexed | Small molecule | 3 mg/m2 | Intravenous |