drugset / Trial / NCT04510285

A Single-Arm Pilot Study of Adjuvant Pembrolizumab Plus Trastuzumab in HER2+ Esophagogastric Tumors With Persistent Circulating Tumor DNA Following Curative Resection

NCT04510285 ↗

Phase 2 Terminated 1 enrolled Memorial Sloan Kettering Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to find out whether treatment with trastuzumab combined with pembrolizumab will improve the clearance of tumor DNA from participants' bodies after surgery.

Timeline

Start
2020-08-10
Primary completion
2022-12-30
Completion
2022-12-30

Outcome

Outcome not reported

Stopped (Enrollment): “Lack of accrual”

Drugs

EvaluationDrugModalityDoseRoute
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous
Subject Trastuzumab Monoclonal antibody 6 mg/kg —