drugset / Trial / NCT04512482
Evaluation of Oral Plaque Removal Utilizing an Adjunct Enzyme Pre-rinse
Phase 2
Completed
46 enrolled
Indiana University
Delta Dental Foundation · collabWater Pik, Inc. · collab
RandomizedCrossoverTriple-blindSupportive care
Summary
This study aims to investigate the impact of a bromelain pre-rinse adjunct on oral plaque removal in orthodontic subjects. The study's null hypothesis states that there is no statistically significant difference in visual plaque scores among orthodontic subjects with or without proteolytic enzyme rinse aid.
Timeline
- Start
- 2018-06-14
- Primary completion
- 2018-07-24
- Completion
- 2019-03-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bromelain | Protein / enzyme biologic | 1 g | — |