Evaluation of Oral Plaque Removal Utilizing an Adjunct Enzyme Pre-rinse

Summary

This study aims to investigate the impact of a bromelain pre-rinse adjunct on oral plaque removal in orthodontic subjects. The study's null hypothesis states that there is no statistically significant difference in visual plaque scores among orthodontic subjects with or without proteolytic enzyme rinse aid.

Timeline

Start

2018-06-14

Primary completion

2018-07-24

Completion

2019-03-04

Outcome

Met primary endpoint

registry analysis (superiority test); Bromelain vs Placebo; p = .044; ANOVA NCT04512482 ↗

Drugs

Indications