drugset / Trial / NCT04515979

Vactosertib in Combination with Pembrolizumab for PD-L1 Positive Non-small Cell Lung Cancer (NSCLC) Subjects

NCT04515979

Phase 2 Terminated 11 enrolled MedPacto, Inc.
NaSingle-groupOpen-labelTreatment

Summary

This is Phase 2, open label, multi-center study to assess safety and efficacy of vactosertib in combination with pembrolizumab as 1st line treatment for subjects with advanced or metastatic, PD-L1 positive, non-small cell lung cancer (NSCLC) who have not previously received systemic therapy for advanced disease and in whom EGFR, ALK, BRAF, ROS1-directed therapy is not indicated.

Timeline

Start
2020-12-17
Primary completion
2024-08-05
Completion
2024-08-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous
Subject Vactosertib Small molecule 300 mg Oral