drugset / Trial / NCT04520178

Effects of 5HTP on the Injured Human Spinal Cord

NCT04520178 ↗

Phase 2/3 Active not recruiting 6 enrolled University of Alberta Wings for Life · collab
RandomizedCrossoverDouble-blindBasic science

Summary

This study will assess how the serotonin precursor, 5-HTP, alter nervous system excitability and motor function in individuals with spinal cord injuries of differing chronicity and severity. Participants will visit the lab on 4 separate occasions where they will be administered four different drugs in a randomized, double-blinded, placebo-controlled crossover design.

Timeline

Start
2020-07-01
Primary completion
2026-05-13
Completion
2026-12-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator 5-Hydroxytryptophan Other / unclassified 50 mg —
Comparator 5-Hydroxytryptophan Other / unclassified 100 mg —
Comparator Carbidopa Unknown 50 mg —

Indications