drugset / Trial / NCT04521049

Tubular Markers in Response to Saxagliptin Therapy

NCT04521049

Phase 4 Completed 80 enrolled Beni-Suef University
RandomizedParallel-groupOpen-labelTreatment

Summary

the study aims to investigate whether treatment with saxagliptin would induce beneficial changes in renal NGAL and L-FABP biomarkers and if they would be used as a tool to identify patients' categories with a particular renal response to DPP-4inhibition. Secondly, to find an association between NGAL and L-FABP, and the relevant renal parameters for both baseline values and rate of changes across defined time points.

Timeline

Start
2019-03-01
Primary completion
2020-03-01
Completion
2020-04-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator SAXAGLIPTIN ANHYDROUS Small molecule 2.5 mg
Comparator SAXAGLIPTIN ANHYDROUS Small molecule 5 mg