drugset / Trial / NCT04521049
Tubular Markers in Response to Saxagliptin Therapy
RandomizedParallel-groupOpen-labelTreatment
Summary
the study aims to investigate whether treatment with saxagliptin would induce beneficial changes in renal NGAL and L-FABP biomarkers and if they would be used as a tool to identify patients' categories with a particular renal response to DPP-4inhibition. Secondly, to find an association between NGAL and L-FABP, and the relevant renal parameters for both baseline values and rate of changes across defined time points.
Timeline
- Start
- 2019-03-01
- Primary completion
- 2020-03-01
- Completion
- 2020-04-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | SAXAGLIPTIN ANHYDROUS | Small molecule | 2.5 mg | — |
| Comparator | SAXAGLIPTIN ANHYDROUS | Small molecule | 5 mg | — |