drugset / Trial / NCT04526782

ENCOrafenib With Binimetinib in bRAF NSCLC

NCT04526782

Phase 2 Active not recruiting 119 enrolled French Cooperative Thoracic Intergroup
Non-randomizedParallel-groupOpen-labelTreatment

Summary

A Phase II study of the BRAF inhibitor Encorafenib in combination with the MEK inhibitor Binimetinib in Patients with BRAFV600E-mutant metastatic Non-small Cell Lung Cancer

Timeline

Start
2021-01-19
Primary completion
2025-07-16
Completion
2026-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Binimetinib Small molecule 45 mg
Subject Encorafenib Small molecule 450 mg