drugset / Trial / NCT04527016

Airway Microbiota Based Treatment of Asthma in Preschool Children

NCT04527016

Phase 4 Completed 120 enrolled Children's Hospital of Fudan University
RandomizedParallel-groupSingle-blindTreatment

Summary

Airway microbiota pattern may related the preschool asthma exacerbation. This is a single-center, randomized-controlled trial, the study will compare the management of preschool wheeze determined by airway microbiota phenotype and blood eosinophils level to the management using current clinical guidelines.

Timeline

Start
2021-10-18
Primary completion
2023-06-15
Completion
2024-06-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Azithromycin Small molecule 10 mg/kg
Subject Budesonide Small molecule 1 mg Inhaled
Subject Fluticasone propionate Other / unclassified 50 ug Inhaled
Comparator Montelukast Other / unclassified 4 mg
Subject Terbutaline Small molecule Inhaled