drugset / Trial / NCT04533997
Hypertonic Saline Therapy in Ambulatory Heart Failure Unit.
Phase 3
Completed
167 enrolled
Puerta de Hierro University Hospital
Instituto de Salud Carlos III · collabSpanish Society of Cardiology · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to compare intravenous furosemide (125 to 250 mg), isolated or in combination with hypertonic saline solution (2.6% to 3.4%) in the outpatient heart failure patient. The hypothesis is that the combination therapy will increase the diuresis volume at 3 hours and improve congestion parameters at 7 days.
Timeline
- Start
- 2021-01-01
- Primary completion
- 2023-05-10
- Completion
- 2023-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hypertonic saline solution | Unknown | 2.6 % | Intravenous |
| Subject | Hypertonic saline solution | Unknown | 3.4 % | Intravenous |
| Background | Furosemide | Other / unclassified | 125 mg | Intravenous |
| Background | Furosemide | Other / unclassified | 250 mg | Intravenous |