Excipient Effect on Drug Absorption in Humans

Phase 0 Completed 12 enrolled University of California, San Francisco Food and Drug Administration (FDA) · collab

RandomizedCrossoverDouble-blindBasic science

Summary

The purpose of this study is to determine if sodium lauryl sulfate (SLS), a non-drug ingredient commonly added in drug products, affect absorption of drugs that are given together with the ingredient. Investigators want to find out if drug absorption is different in people taking the drug alone compared to people taking the drug with low and high amounts of sodium lauryl sulfate at the same time.

Timeline

Start: 2023-01-31
Primary completion: 2025-06-18
Completion: 2025-08-18

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Fexofenadine	Unknown	120 mg	Oral

Indications

No indication recorded.