Aerosoliserat DNase for Treatment of Respiratory Failure in Severe COVID-19

Summary

Recent observations have suggested a role of neutrophil extracellular traps (NETs) in the pathophysiology of severe COVID-19. The aim of the study is to assess efficacy and safety of aerosolized DNase I to remove NETs and decrease respiratory distress in patients with COVID-19.

Timeline

Start

2020-06-04

Primary completion

2022-01-11

Completion

2023-01-06

Drugs

Indications