drugset / Trial / NCT04554589

The Off Label Use of Glycopyrrolate in the Adults Intensive Care Unit.

NCT04554589

Phase 1 Unknown 80 enrolled Tanta University
RandomizedParallel-groupTriple-blindTreatment

Summary

Tracheostomized patients in the ICU can have excessive tracheal secretions due to various causes as hyperactive airway, irritation of the mucus producing cells and inhibition of the ciliary functions. Excessive secretions will necessitate frequent suctions which carries the risk of tracheostomy tube obstruction if not managed properly. Excessive tracheal secretions may prolong the ICU stay, increase the nurses workload and increase patients morbidity and mortality. This clinical trial hypothesizes that the use of glycopyrrolate may decrease the tracheal secretions and hence avoid such complications.

Timeline

Start
2020-09-14
Primary completion
2021-02-10
Completion
2021-04-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Glycopyrrolate Small molecule 0.2 mg Intravenous

Indications

No indication recorded.