drugset / Trial / NCT04557397
Fruquintinib CYP3A Inhibitor and Inducer Study
Non-randomizedCrossoverOpen-labelBasic science
Summary
A study to assess the effect of itraconazole, a strong CYP3A inhibitor, and the effect of rifampin, a strong CYP3A inducer, on the pharmacokinetics of fruquintinib in healthy subjects.
Timeline
- Start
- 2020-09-02
- Primary completion
- 2020-10-18
- Completion
- 2020-10-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fruquintinib | Small molecule | — | Oral |
| Subject | Itraconazole | Small molecule | — | — |
| Subject | Rifampin | Small molecule | — | — |
Indications
No indication recorded.