drugset / Trial / NCT04558463

The Effectivity and Safety of Favipiravir Compared to Oseltamivir as Adjuvant Therapy for COVID-19

NCT04558463

Phase 3 Unknown 100 enrolled Indonesia University
RandomizedParallel-groupOpen-labelTreatment

Summary

This study aims to analyze the effectiveness and safety of Avigan® (favipiravir) compared to Oseltamivir as an adjuvant therapy among adult COVID-19 patients. This study will be conducted in a hospital setting, recruiting adult COVID-19 patients with mild, moderate, and severe symptoms. Subjects will be randomly given Favipiravir or Oseltamivir as an adjuvant therapy to standard COVID-19 treatment. Patients will be followed up for 21 days after the first dose of intervention given. The primary outcomes of this study are the improvement of radiology results and RT PCR negative conversion during follow up. The secondary outcomes are adverse events, hospital length of stay (LOS), and Case fatality rate (CFR)

Timeline

Start
2020-04-16
Primary completion
2020-09-30
Completion
2020-10-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Favipiravir Small molecule 600 mg
Comparator Oseltamivir Small molecule 75 mg

Indications