drugset / Trial / NCT04558697

Use of Vagitories Based on St. John's Wort, Tea Tree Oil and Shepherd's Purse in the Treatment of Vaginal Inflammation

NCT04558697

RandomizedParallel-groupOpen-labelTreatment

Summary

There are more and more herbal preparations that are used for the purpose of treatment and improvement of the clinical picture of vaginitis by patients themselves, but also by healthcare professionals. Plant species, St. John's wort, chamomile, calendula, yarrow, shepherd's purse and tea tree oil are well known for there anti-inflammatory, antimicrobial and wound healing activity. This paper presents the results of a clinical study in which three herbal formulations/vagitories, based on extracts of above mentioned plant species, were investigated for their effectiveness on non-specific vaginitis. This was randomized controlled clinical study that included 210 women with diagnosed non-specific vaginitis. Patients were divided into two basic groups, women in reproductive stage and postmenopausal stage. Three subgroups, containing approximately 30 patients each, received one of three vagitorie formulations for 5 days during which the effects on subjective and objective symptoms were monitored.

Timeline

Start
2019-03-21
Primary completion
2019-06-21
Completion
2019-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Hyperici extractum oleosum Unknown 32 % Other
Subject Shepherd's Purse extractum oleosum Unknown 5.5 % Other
Subject tea tree oil Unknown 200 mg Other

Indications