drugset / Trial / NCT04558853

Clinical Study of Autologous Natural Killer Cells in Multiple Myeloma

NCT04558853 ↗

Phase 1 Unknown 12 enrolled Karolinska University Hospital
NaSingle-groupOpen-labelTreatment

Summary

Multiple Myeloma (MM) is a lethal disease and at present no available treatment method seems to prevent the disease from progressing or relapsing in the long term. NK cells have a relatively high cytotoxic capacity and an anti tumour effect, suggesting a potential as a treatment of MM.This is a phase I, first-in-human, therapeutic exploratory study, where no benefits for the patients can be guaranteed. However, the theoretical implication is that the infused cells may have a positive antitumour effect for the participating individuals.

Timeline

Start
2014-01-01
Primary completion
2021-12-31
Completion
2022-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject autologous NK cells Cell therapy 5 cells/kg Intravenous
Subject autologous NK cells Cell therapy 50 cells/kg Intravenous
Subject autologous NK cells Cell therapy 100 cells/kg Intravenous

Indications