drugset / Trial / NCT04558853
Clinical Study of Autologous Natural Killer Cells in Multiple Myeloma
NaSingle-groupOpen-labelTreatment
Summary
Multiple Myeloma (MM) is a lethal disease and at present no available treatment method seems to prevent the disease from progressing or relapsing in the long term. NK cells have a relatively high cytotoxic capacity and an anti tumour effect, suggesting a potential as a treatment of MM.This is a phase I, first-in-human, therapeutic exploratory study, where no benefits for the patients can be guaranteed. However, the theoretical implication is that the infused cells may have a positive antitumour effect for the participating individuals.
Timeline
- Start
- 2014-01-01
- Primary completion
- 2021-12-31
- Completion
- 2022-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | autologous NK cells | Cell therapy | 5 cells/kg | Intravenous |
| Subject | autologous NK cells | Cell therapy | 50 cells/kg | Intravenous |
| Subject | autologous NK cells | Cell therapy | 100 cells/kg | Intravenous |