drugset / Trial / NCT04558931
Clinical Trial for Autologus NK Cells Alone or in Combination With Isatuximab as Maintenance for Multiple Myeloma
Phase 2
Recruiting
62 enrolled
Karolinska Institutet
Sanofi · collabXNK Therapeutics AB, Sweden · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Prospective, single center, randomized, open label, parallel group, 2-arm study assessing the clinical benefit in term of enhancement of overall response rate of Isatuximab in combination with CellProtect as compared to Isatuximab for the treatment of patients with newly diagnosed multiple myeloma who are eligible for stem cell transplantation (SCT) as maintenance after SCT.
Timeline
- Start
- 2021-06-02
- Primary completion
- 2027-12-31
- Completion
- 2032-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Isatuximab | Monoclonal antibody | 10 mg/kg | Intravenous |
| Subject | autologous NK cell | Cell therapy | 3e+07 cells/kg | Intravenous |
| Subject | autologous NK cell | Cell therapy | 1e+08 cells/kg | Intravenous |