HYDEAL-D® Application for Promoting the Restoration of Sexual Function in the Postpartum Period

Summary

During postpartum and lactation, vaginal epithelium tends to have an impaired degree of hydration and lubrication. This may lead to vaginal dryness, burning sensation dyspareunia or itching, which negatively affect the sexual function of puerperal women. This study aimed to evaluate the efficacy of HYDEAL-D® vaginal gel (HYALOGYN®, Fidia Farmaceutici, Abano Terme, Italy) application on promoting the restoration of sexual function in the postpartum period.

Timeline

Start

2016-09-01

Primary completion

2020-05-01

Completion

2020-09-01

Outcome

Met primary endpoint

paper FSFI) total score (+15.1 ± 11.9 vs +6.5 ± 8.9, p < 0.001) PMID 34477473 ↗

paper the results of our study demonstrated that hyaluronic acid derivative vaginal gel (Hydeal-D) was able to improve sexual function PMID 34477473 ↗

Publications

• Results Gustavino C, Sala P, Cusini N, Gravina B, Ronzini C, Marcolin D, Vellone VG, Paudice M, Nappi R, Costantini S, Ferrero S, Barra F. Efficacy and safety of prolonged-release hyaluronic acid derivative vaginal application in the postpartum period: a prospective randomised clinical trial. Ann Med. 2021 Dec;53(1):1589-1597. doi: 10.1080/07853890.2021.1974083.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	HYALOGYN	Other / unclassified	2 %	Other

Indications