drugset / Trial / NCT04565483
Predictive Signature of Benralizumab Response
Phase 4
Recruiting
220 enrolled
Nantes University Hospital
AstraZeneca · collabMinistère de la Santé - France · collab
NaSingle-groupOpen-labelOther
Summary
The objective of the study is to establish the predictive value of early blood gene expression signature of Benralizumab response associated with a significant reduction of the number of exacerbations in treated severe asthmatic patients. This trial is a French, multicenter and no-randomized trial. Patients enrolled will be clinically followed for 16 months (the treatment period: 12 months and 1 month follow-up; 6 clinical visit on site and in phone call at 13 months)
Timeline
- Start
- 2021-10-11
- Primary completion
- 2026-10
- Completion
- 2026-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Benralizumab | Monoclonal antibody | — | — |