drugset / Trial / NCT04568772
Study to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy Volunteers
RandomizedCrossoverOpen-labelOther
Summary
The aim of this study is to evaluate the influence of tegoprazan on the pharmacokinetics of proguanil in healthy volunteers.
Timeline
- Start
- 2020-11-25
- Primary completion
- 2021-07-08
- Completion
- 2021-08-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Esomeprazole | Small molecule | 40 mg | Oral |
| Subject | Proguanil | Small molecule | 100 mg | Oral |
| Subject | Tegoprazan | Other / unclassified | 50 mg | Oral |
| Subject | Vonoprazan | Other / unclassified | 20 mg | Oral |
| Background | Atovaquone | Small molecule | 250 mg | Oral |