drugset / Trial / NCT04583254
Hypofractionated External-beam RadiOtherapy for Intact Cervical Cancer (HEROICC-Trial): A Feasibility Study
Phase 2
Recruiting
48 enrolled
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Academic Medical Organization of Southwestern Ontario · collab
RandomizedParallel-groupOpen-labelScreening
Summary
External radiation given in 25 fractions or so together with weekly chemotherapy and followed by 3 or 4 fractions of brachytherapy is the standard of care for patients with locally advanced cervical cancer. This study investigates the role of shortened external radiotherapy regimen (hypofractionated radiotherapy) by randomizing patients to this experimental regimen versus the standard of care.The purpose of this study is to access the feasibility of patient accrual to this trial in the Canadian setting and to provide an initial evaluation of cancer response and treatment tolerability.
Timeline
- Start
- 2021-02-04
- Primary completion
- 2023-12-14
- Completion
- 2028-12-14
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Cisplatin | Other / unclassified | 40 mg/m2 | — |