drugset / Trial / NCT04583254

Hypofractionated External-beam RadiOtherapy for Intact Cervical Cancer (HEROICC-Trial): A Feasibility Study

NCT04583254 ↗

RandomizedParallel-groupOpen-labelScreening

Summary

External radiation given in 25 fractions or so together with weekly chemotherapy and followed by 3 or 4 fractions of brachytherapy is the standard of care for patients with locally advanced cervical cancer. This study investigates the role of shortened external radiotherapy regimen (hypofractionated radiotherapy) by randomizing patients to this experimental regimen versus the standard of care.The purpose of this study is to access the feasibility of patient accrual to this trial in the Canadian setting and to provide an initial evaluation of cancer response and treatment tolerability.

Timeline

Start
2021-02-04
Primary completion
2023-12-14
Completion
2028-12-14

Drugs

EvaluationDrugModalityDoseRoute
Background Cisplatin Other / unclassified 40 mg/m2 —

Indications