drugset / Trial / NCT04586816
Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Recent research has reported that the maple leaf extract exhibits anti-aging effects by inhibiting elastase activity, thereby preventing the breakdown of elastin and interfering with the formation of wrinkles. Red maple leaf extract contains phenolic compounds known as glucitol-core-containing gallotannins (GCGs) which help reduce the appearance of wrinkles and may decrease skin inflammation, dark spots and pigmentation. The objective of this study is to examine the effects of topical Maplifa on the cosmetic appearance of facial lines, redness and skin tone.
Timeline
- Start
- 2019-09-10
- Primary completion
- 2020-01-15
- Completion
- 2020-01-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Maplifa | Unknown | 1 % | Topical |
| Subject | Maplifa | Unknown | 5 % | Topical |