NCT04588740: Inorganic Nitrate: Sex Differences in Muscle Contractile Function and Efficiency

Summary

Dietary inorganic nitrate, in the form of beet root juice, is a nutritional intervention, considered to be an exercise enhancer due to its capacity to increase Nitric Oxide (NO) bioavailability. Increasing NO bioavailability has been associated with improved mitochondrial respiration, muscle tissue perfusion and contractile function which may lead to improved exercise capacity. However, the majority of the literature is on male subjects. This limits the applicability of this supplement in females. Therefore, our project aims to determine sex-differences and the specific sex-response across the menstrual cycle of dietary nitrate supplementation on exercise efficiency, strength and fatigue resistance.

Timeline

Start: 2020-01-20
Primary completion: 2023-12-30
Completion: 2023-12-30

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	concentrated beet root juice	Other / unclassified	6.2 mmol	—

Indications

No indication recorded.