drugset / Trial / NCT04588844
Effect of Growth Hormone Injection on the IVF/ICSI Outcome of Patients With Poor Ovarian Reserve.
Unknown
200 enrolled
Shandong University
RenJi Hospital · collabThe Second Hospital of Hebei Medical University · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Declined fertility and ovarian reserve in older women are associated with lower density of Growth hormone (GH) receptors and dysregulation in GH secretion. GH can regulate the expression of growth hormone receptor and strengthen the function of mitochondria, which could improve the quality of the female oocyte. In this study, a prospective randomized control will be conducted to explore the effect of GH adjuvant therapy on clinical outcome of in vitro fertilization.
Timeline
- Start
- 2020-12-01
- Primary completion
- 2022-03-20
- Completion
- 2023-03-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Somatropin | Protein / enzyme biologic | 3 mg | — |