drugset / Trial / NCT04588987

Neoadjuvant Carilizumab and Apatinib for Recurrent High-Grade Glioma

NCT04588987 ↗

Phase 2 Unknown 60 enrolled Sun Yat-sen University
RandomizedParallel-groupOpen-labelTreatment

Summary

GBM is the most common intracranial tumor in adults, accounting for about 40% of all primary intracranial tumors.Although surgery, radiotherapy and chemotherapy have been used, the prognosis of glioma patients is still very poor. The study aim to Evaluate the Safety and efficiency of Using the neoadjuvant therapy with Carilizumab and Apatinib in patients with Recurrent High-Grade Glioma.

Timeline

Start
2020-10
Primary completion
2023-10
Completion
2024-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Camrelizumab Monoclonal antibody — —
Subject Rivoceranib Small molecule — —