drugset / Trial / NCT04592653

Less Frequent IV Dosing & Tumor Microenvironment (TME) Study of Nemvaleukin Alfa (ALKS 4230) Monotherapy and in Combination With Pembrolizumab (ARTISTRY-3)

NCT04592653

Phase 1/2 Active not recruiting 78 enrolled Mural Oncology, Inc
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The study will be conducted in 2 cohorts. A single-center design for the tumor microenvironment (TME) cohort (Cohort 1), and a multicenter design for the less frequent intravenous (IV) dosing cohort (Cohort 2).

Timeline

Start
2020-09-30
Primary completion
2024-07
Completion
2024-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Nemvaleukin Alfa Protein / enzyme biologic Intravenous
Subject Pembrolizumab Monoclonal antibody Intravenous

Indications