drugset / Trial / NCT04594642

A Study of AZD0486 in Subjects With B-Cell Non-Hodgkin Lymphoma

NCT04594642

Phase 1 Active not recruiting 226 enrolled AstraZeneca
NaSequentialOpen-labelTreatment

Summary

This phase 1 study will investigate the safety, tolerability, pharmacokinetic, pharmacodynamic, and clinical activity of AZD0486, a CD19 x CD3 T-cell engaging bispecific antibody, in subjects with B-cell non-Hodgkin lymphoma (B-NHL).

Timeline

Start
2021-03-02
Primary completion
2028-06-19
Completion
2028-06-19

Drugs

EvaluationDrugModalityDoseRoute
Subject Surovatamig Protein / enzyme biologic Intravenous