drugset / Trial / NCT04601324
Allergic Rhinitis Combination Pharmacotherapy Efficacy Study
RandomizedParallel-groupSingle-blindTreatment
Summary
Combination pharmacotherapy is often used in people who have failed mono-therapies in managing their bothersome allergic rhinitis symptoms . However, there is a paucity of research indicating the most effective combination therapies in managing allergic rhinitis. This study aims to evaluate the efficacy of oral antihistamine (rupatadine) combined with nasal steroid (fluticasone propionate) compared to a well-studied combination therapy of nasal steroid with nasal antihistamine spray (MP-AzeFlu).
Timeline
- Start
- 2020-12-15
- Primary completion
- 2021-06-01
- Completion
- 2021-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Azelastine | Small molecule | 137 mg | Intranasal |
| Subject | Fluticasone propionate | Other / unclassified | 50 ug | Intranasal |
| Subject | Rupatadine | Small molecule | 10 mg | Oral |