Targeting the Gut-brain Axis to Facilitate Weight Loss in High Fat Diet Consumers

Phase 4 Terminated 64 enrolled Yale University National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · collab

RandomizedParallel-groupQuadruple-blindBasic science

Summary

The primary objective is to test if fat intake moderates the ability of oleoylethanolamide (OEA) to improve weight loss maintenance after the LEARN® weight loss program.

Timeline

Start: 2021-04-06
Primary completion: 2024-10-04
Completion: 2024-10-04

Outcome

Outcome not reported

Stopped: “PI changed institutions”

Publications

Fang X, Davis X, Flack KD, Duncan C, Li F, White M, Grilo C, Small DM. Dietary adaptation for weight loss maintenance at Yale (DAWLY): Protocol and predictions for a randomized controlled trial. Front Nutr. 2022 Jul 28;9:940064. doi: 10.3389/fnut.2022.940064. eCollection 2022.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Oleoylethanolamide	Other / unclassified	90 %	—