Mesenchymal Stem Cell Therapy of Dry Eye Disease in Patients With Sjögren's Syndrome

Summary

AMASS is a double-blinded randomized clinical trial with the purpose of investigating whether injection of allogeneic adipose-derived mesenchymal stem cells (ASCs) into the lacrimal gland (LG) results in increased ocular comfort compared to placebo.

Timeline

Start

2020-11-03

Primary completion

2022-12-01

Completion

2023-01-01

Publications

• Larsen AC, Moller-Hansen M, Wiencke AK, Terslev L, Torp-Pedersen S, Heegaard S. Ultrasound-Guided Transcutaneous Injection in the Lacrimal Gland: A Description of Sonoanatomy and Technique. J Ocul Pharmacol Ther. 2023 May;39(4):275-278. doi: 10.1089/jop.2022.0156. Epub 2023 Mar 21.

Drugs

Indications