drugset / Trial / NCT04617652
Smooth Extubation With Magnesium Sulphate for General Anesthesia With Endotracheal Intubation
RandomizedParallel-groupDouble-blindPrevention
Summary
Tracheal extubation is a critical event in the anaesthetic management of patients undergoing general anaesthesia with endotracheal intubation for elective procedures. It the state of art to provide suitable conditions for smooth extubation and avoid coughing, bucking, straining and/or laryngospasm. Several methods have been described to provide a smooth extubation, including the use of remifentanil infusion, dexmedetomidine or fentanyl. Because of its anti-inflammatory and analgesic effects and lack of respiratory depressant actions, magnesium sulphate could be an attractive alternative.
Timeline
- Start
- 2020-08-01
- Primary completion
- 2021-02-01
- Completion
- 2021-04-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Magnesium Sulfate | Other / unclassified | 1 g | — |
Indications
No indication recorded.