drugset / Trial / NCT04627064
ABEMA Alone or in COMBO With MK-6482
Phase 1
Completed
11 enrolled
Dana-Farber Cancer Institute
Eli Lilly and Company · collabNational Cancer Institute (NCI) · collab
Non-randomizedSequentialOpen-labelTreatment
Summary
This research study will assess whether abemaciclib alone or in combination with MK-6482 are safe and effective in slowing down the growth of clear cell renal cell carcinoma (ccRCC). The names of the study drugs in this investigational combination are: * Abemaciclib * MK-6482
Timeline
- Start
- 2020-12-31
- Primary completion
- 2024-02-09
- Completion
- 2024-08-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Abemaciclib | Small molecule | — | Oral |
| Subject | Belzutifan | Small molecule | — | Oral |