drugset / Trial / NCT04633122
A Study to Assess DCC-2618 and Sunitinib in Patients With Advanced GIST After Treatment With Imatinib
RandomizedParallel-groupOpen-labelTreatment
Summary
the primary objective of this study is to assess the efficacy (progression-free survival,PFS) of DCC-2618 (ripretinib, ZL-2307) and sunitinib in patients with advanced gastrointestinal stromal tumors after treatment with imatinib. This study will enroll approximately 98 subjects in around 18 sites in China mainland, and all subjects will be receiving DCC-2618 or Sunitinib in equal chance as treatment.
Timeline
- Start
- 2020-11-25
- Primary completion
- 2022-07-20
- Completion
- 2022-07-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ripretinib | Small molecule | 150 mg | Oral |
| Comparator | Sunitinib | Small molecule | 50 mg | — |