drugset / Trial / NCT04633122

A Study to Assess DCC-2618 and Sunitinib in Patients With Advanced GIST After Treatment With Imatinib

NCT04633122

Phase 2 Completed 108 enrolled Zai Lab (Shanghai) Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

the primary objective of this study is to assess the efficacy (progression-free survival,PFS) of DCC-2618 (ripretinib, ZL-2307) and sunitinib in patients with advanced gastrointestinal stromal tumors after treatment with imatinib. This study will enroll approximately 98 subjects in around 18 sites in China mainland, and all subjects will be receiving DCC-2618 or Sunitinib in equal chance as treatment.

Timeline

Start
2020-11-25
Primary completion
2022-07-20
Completion
2022-07-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Ripretinib Small molecule 150 mg Oral
Comparator Sunitinib Small molecule 50 mg