drugset / Trial / NCT04638881

Magnesium for Peroral Endoscopic Myotomy

NCT04638881

Phase 2 Completed 92 enrolled Stanford University
RandomizedParallel-groupDouble-blindTreatment

Summary

Postoperative pain after peroral endoscopic myotomy occurs due to involuntary esophageal smooth muscle spasms. Magnesium has antispasmodic properties as a smooth muscle relaxant. This study hypothesizes that among patients having peroral endoscopic myotomy, magnesium will decrease postoperative esophgeal pain as measured by the esophageal symptoms questionnaire, while decreasing perioperative opioid requirements.

Timeline

Start
2020-12-28
Primary completion
2023-04-13
Completion
2023-04-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Magnesium Sulfate Other / unclassified 25 mg/kg