drugset / Trial / NCT04641442

Study to Evaluate the Efficacy, Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases, Including NLRC4-GOF, XIAP Deficiency, or CDC42 Mutations

NCT04641442

Phase 2 Active not recruiting 17 enrolled Novartis Pharmaceuticals
RandomizedParallel-groupTriple-blindTreatment

Summary

This study is a Phase 2 trial designed to evaluate the clinical efficacy, safety, and tolerability of MAS825 in patients with NLRC4-GOF, XIAP deficiency, or CDC42 mutations.

Timeline

Start
2020-12-18
Primary completion
2025-10-14
Completion
2032-04-07

Drugs

EvaluationDrugModalityDoseRoute
Subject MAS825 Monoclonal antibody