drugset / Trial / NCT04649112

Dose-escalation Study of Safety of PBCAR19B in Participants With CD19-expressing Malignancies

NCT04649112 ↗

Phase 1 Completed 13 enrolled Precision BioSciences, Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a Phase 1, nonrandomized, open-label, single-dose, dose-escalation, and dose-expansion study to evaluate the safety and clinical activity of PBCAR19B in adult study participants with CD-19 expressing malignancies.

Timeline

Start
2021-06-16
Primary completion
2022-12-22
Completion
2023-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject PBCAR19B Cell therapy — Intravenous