drugset / Trial / NCT04649723

Drug-Drug Interaction of SHR1459 With a Strong CYP3A Index Inducer (Rifampicin)

NCT04649723

Phase 1 Completed 20 enrolled Jiangsu HengRui Medicine Co., Ltd.
Non-randomizedSequentialOpen-labelTreatment

Summary

This drug-drug interaction (DDI) study had been designed to investigate the effect of a strong CYP 3A index fan-inducer rifampicin on the pharmacokinetics of SHR1459 in Chinese healthy volunteers.

Timeline

Start
2020-11-24
Primary completion
2020-12-14
Completion
2020-12-14

Drugs

EvaluationDrugModalityDoseRoute
Subject EDRALBRUTINIB Small molecule 200 mg Oral
Subject Rifampin Small molecule 600 mg Oral

Indications

No indication recorded.