drugset / Trial / NCT04655040
Estimation of the Effect of Multiple Dose Ritlecitinib (PF-06651600) on the Pharmacokinetics of a Single Dose of Caffeine in Healthy Participants
NaSingle-groupOpen-labelBasic science
Summary
This will be a Phase 1, 2 period, fixed sequence, multiple-dose, open-label study of the effect of ritlecitinib on caffeine PK in healthy participants. Approximately 12 healthy male and/or female participants will be enrolled in the study.
Timeline
- Start
- 2020-12-18
- Primary completion
- 2021-03-05
- Completion
- 2021-03-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Caffeine | Small molecule | 100 mg | Oral |
| Subject | Ritlecitinib | Small molecule | 200 mg | Oral |
Indications
No indication recorded.