drugset / Trial / NCT04667078

REperfusion With P2Y12 Inhibitors in Addition to mEchanical thRombectomy for perFUsion Imaging Selected Acute Stroke patiEnts

NCT04667078 ↗

RandomizedParallel-groupSingle-blindTreatment

Summary

The main objective is to evaluate the efficacy of IV administration of the P2Y12 inhibitor (cangrelor) in addition to mecanich thrombectomy and WMD versus mecanich thrombectomy and WMD alone on the functional prognosis at 3 months, in patients with acute ischemic stroke eligible for mecanich thrombectomy on the basis of infusion imaging between 0 and 24 hours after the onset of symptoms.

Timeline

Start
2022-03-02
Primary completion
2026-12-21
Completion
2027-12-21

Outcome

Outcome not reported

Stopped: “The study was terminated prematurely due to futility based on a pre-specified interim analysis, awaiting for the last visit of the last patient”

Drugs

EvaluationDrugModalityDoseRoute
Subject Cangrelor Small molecule 4 ug/kg Intravenous

Indications