drugset / Trial / NCT04667078
REperfusion With P2Y12 Inhibitors in Addition to mEchanical thRombectomy for perFUsion Imaging Selected Acute Stroke patiEnts
Phase 3
Suspended
368 enrolled
Fondation Ophtalmologique Adolphe de Rothschild
Ministry of Health, France · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
The main objective is to evaluate the efficacy of IV administration of the P2Y12 inhibitor (cangrelor) in addition to mecanich thrombectomy and WMD versus mecanich thrombectomy and WMD alone on the functional prognosis at 3 months, in patients with acute ischemic stroke eligible for mecanich thrombectomy on the basis of infusion imaging between 0 and 24 hours after the onset of symptoms.
Timeline
- Start
- 2022-03-02
- Primary completion
- 2026-12-21
- Completion
- 2027-12-21
Outcome
Outcome not reported
Stopped: “The study was terminated prematurely due to futility based on a pre-specified interim analysis, awaiting for the last visit of the last patient”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cangrelor | Small molecule | 4 ug/kg | Intravenous |