drugset / Trial / NCT04668768

HM-178: Assessing Methods for Improvement in Methotrexate Toxicity Management and Detection of Central Nervous System Involvement of Aggressive Lymphoma

NCT04668768 ↗

Phase 2 Suspended 3 enrolled Fox Chase Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

This is a study to use glucarpidase prophylactically to treat methotrexate induced toxicities in lymphoma patients with cerebral involvement.

Timeline

Start
2021-04-16
Primary completion
2024-12
Completion
2025-04

Outcome

Outcome not reported

Stopped (Enrollment): “To be terminated due to slow accrual, patient still in follow up”

Drugs

EvaluationDrugModalityDoseRoute
Subject Glucarpidase Protein / enzyme biologic — —

Indications