drugset / Trial / NCT04677361

Feasibility Study on Expandion of MILs From NSCLC and SCLC Patients and Infusion With Pembrolizumab

NCT04677361

NaSingle-groupOpen-labelTreatment

Summary

Marrow infiltrating lymphocytes (MILs™) are a novel method of adoptive cell therapy that provide an activated, polyclonal population of autologous tumor-specific T cells derived from the bone marrow. MILs™ in this study will be used to treat small cell lung cancer (SCLC) that has become resistant to chemotherapy and radiation.

Timeline

Start
2021-10
Primary completion
2023-10
Completion
2024-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Marrow infiltrating lymphocytes Cell therapy 2e+08 cells Other
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous