drugset / Trial / NCT04678648

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

NCT04678648 ↗

Phase 1 Recruiting 134 enrolled RasCal Therapeutics, Inc.
NaSequentialOpen-labelTreatment

Summary

RSC-101 is a Phase 1a/1b clinical trial of RSC-1255 in adult study participants with advanced solid tumor malignancies who are intolerant of existing therapies known to provide clinical benefit, have disease that has progressed after standard therapy, or have previously failed other therapies. The study has two phases. The purpose of Phase 1a (Dose Escalation) is to confirm the appropriate treatment dose and Phase 1b (Dose Expansion) is to characterize the safety and efficacy of RSC-1255.

Timeline

Start
2021-03-03
Primary completion
2026-12-15
Completion
2027-01-30

Drugs

EvaluationDrugModalityDoseRoute
Subject RSC-1255 Small molecule — Oral