drugset / Trial / NCT04683250

Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities

NCT04683250 ↗

Non-randomizedSequentialOpen-labelTreatment

Summary

Phase 1 and 2 trial to study the safety, pharmacokinetics, and efficacy of TAS0953/HM06 in patients with advanced solid tumors with RET gene abnormalities. Phase 1 aims to determine the Maximum Tolerated Dose (MTD) and identify the Recommended Phase 2 Dose (RP2D) to be used in phase 2.

Timeline

Start
2020-12-16
Primary completion
2030-03
Completion
2031-03

Drugs

EvaluationDrugModalityDoseRoute
Subject TAS0953/HM06 Unknown 20 mg Oral
Subject TAS0953/HM06 Unknown 20 mg Oral