drugset / Trial / NCT04683250
Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities
Non-randomizedSequentialOpen-labelTreatment
Summary
Phase 1 and 2 trial to study the safety, pharmacokinetics, and efficacy of TAS0953/HM06 in patients with advanced solid tumors with RET gene abnormalities. Phase 1 aims to determine the Maximum Tolerated Dose (MTD) and identify the Recommended Phase 2 Dose (RP2D) to be used in phase 2.
Timeline
- Start
- 2020-12-16
- Primary completion
- 2030-03
- Completion
- 2031-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | TAS0953/HM06 | Unknown | 20 mg | Oral |
| Subject | TAS0953/HM06 | Unknown | 20 mg | Oral |