drugset / Trial / NCT04683640
Latent Aging Mechanisms in Pain and Sleep
Phase 2
Completed
33 enrolled
University of Florida
National Institute on Aging (NIA) · collabThorne HealthTech, Inc · collab
RandomizedParallel-groupDouble-blindBasic science
Summary
Chronic pain is a serious public health problem in older adults depending on the pain condition, and the capacity to sleep properly changes with age. Given the potential mechanistic role of GABA (gamma-aminobutyric acid) in both conditions, based on our preliminary data, this proposal will determine the effect of oral GABA administration in sleep quality and pain in older adults with chronic pain and sleep disorders as well as to characterize the potential neurobiological mechanisms involved in both illnesses.
Timeline
- Start
- 2021-04-02
- Primary completion
- 2024-05-30
- Completion
- 2024-05-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gamma-Aminobutyric Acid | Small molecule | 500 mg | Oral |