Effect of PDE5 Inhibition on Adipose Metabolism in Humans

Summary

This is a randomized, double-blinded, placebo-controlled study of the effects of PDE5 inhibition with tadalafil on adipose tissue in obese individuals. Adipose metabolism will be measured using magnetic resonance imaging (MRI) scans and by aspirating a small amount of adipose to measure gene expression.

Timeline

Start

2021-03-16

Primary completion

2025-06-20

Completion

2025-06-24

Drugs

Indications