drugset / Trial / NCT04690322

POCUS: Hemostatic Potential and Joint Health in Patients With Severe Hemophilia A on Novel Replacement Therapies

NCT04690322 ↗

RandomizedParallel-groupOpen-labelTreatment

Summary

This is a prospective, randomized control trial in which each patient will be randomly assigned to receive either extended half-life factor VIII based replacement therapy or non-FVIII based replacement therapy, which are both standard of care treatment for persons with Hemophilia A.

Timeline

Start
2021-04-15
Primary completion
2027-07
Completion
2027-07

Outcome

Outcome not reported

Stopped (Enrollment): “Due to COVID-19 pandemic, recruitment was temporarily put on hold. We are withdrawing this registration due to a recent amendment to the protocol that includes major changes to data elements. A new registration will be submitted for the new protocol.”

Drugs

EvaluationDrugModalityDoseRoute
Comparator ANTIHEMOPHILIC FACTOR, PEGYLATED (MW 20000) HUMAN SEQUENCE RECOMBINANT Protein / enzyme biologic — —
Comparator Efmoroctocog Alfa Protein / enzyme biologic — —
Comparator Emicizumab Monoclonal antibody — —

Indications